Mark F McCarty Selected Research

Vegan Diet (Diet, Vegan)

4/2021	Age-adjusted mortality from pancreatic cancer increased NINE-FOLD in japan from 1950 to 1995 - Was a low-protein quasi-vegan diet a key factor in their former low risk?
9/2014	GCN2 and FGF21 are likely mediators of the protection from cancer, autoimmunity, obesity, and diabetes afforded by vegan diets.
1/2012	Minimizing the cancer-promotional activity of cox-2 as a central strategy in cancer prevention.
10/2011	mTORC1 activity as a determinant of cancer risk--rationalizing the cancer-preventive effects of adiponectin, metformin, rapamycin, and low-protein vegan diets.
1/2005	The low-AGE content of low-fat vegan diets could benefit diabetics - though concurrent taurine supplementation may be needed to minimize endogenous AGE production.
1/2004	An elevation of triglycerides reflecting decreased triglyceride clearance may not be pathogenic -- relevance to high-carbohydrate diets.
6/2002	Favorable impact of a vegan diet with exercise on hemorheology: implications for control of diabetic neuropathy.

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Mark F McCarty Research Topics

Disease

39	Neoplasms (Cancer) 04/2021 - 09/2003
31	Insulin Resistance 01/2016 - 06/2002
14	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2022 - 09/2010
14	Hypertension (High Blood Pressure) 01/2022 - 01/2004
14	Atherosclerosis 12/2020 - 01/2005
13	Inflammation (Inflammations) 04/2022 - 05/2003
13	Type 2 Diabetes Mellitus (MODY) 12/2021 - 06/2002
12	Heart Failure 01/2022 - 01/2005
11	Stroke (Strokes) 01/2016 - 06/2003
9	Hypertrophy 03/2021 - 01/2004
9	Obesity 01/2018 - 01/2005
8	Myocardial Infarction 12/2020 - 01/2004
7	Hypoxia (Hypoxemia) 08/2020 - 12/2004
7	Coronary Disease (Coronary Heart Disease) 05/2017 - 01/2004
6	Alzheimer Disease (Alzheimer's Disease) 02/2021 - 01/2004
6	Weight Gain 10/2018 - 01/2004
6	Vascular Diseases (Vascular Disease) 01/2015 - 09/2003
6	Weight Loss (Weight Reduction) 10/2011 - 06/2002
5	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 01/2006
5	Prostatic Neoplasms (Prostate Cancer) 02/2017 - 12/2004
5	Hyperglycemia 04/2015 - 01/2004
5	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 05/2009 - 01/2004
4	Acquired Immunodeficiency Syndrome (AIDS) 08/2020 - 01/2005
4	Cardiovascular Diseases (Cardiovascular Disease) 05/2017 - 06/2009
4	Neoplasm Metastasis (Metastasis) 08/2016 - 06/2006
4	Thinness 12/2015 - 07/2010
4	Fibrosis (Cirrhosis) 10/2011 - 01/2005
3	Osteolysis 04/2022 - 06/2006
3	Non-alcoholic Fatty Liver Disease 01/2022 - 10/2011
3	Cardiomegaly (Heart Hypertrophy) 01/2021 - 01/2015
3	Vascular Calcification 01/2021 - 03/2014

Drug/Important Bio-Agent (IBA)

17	AntioxidantsIBA 01/2022 - 01/2004
16	Insulin (Novolin)FDA Link 12/2021 - 06/2002
14	Glucose (Dextrose)FDA LinkGeneric 12/2021 - 06/2002
14	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2021 - 06/2002
13	NF-kappa B (NF-kB)IBA 01/2022 - 12/2004
13	Metformin (Glucophage)FDA LinkGeneric 08/2018 - 01/2004
13	Vitamin D FDA LinkGeneric 02/2017 - 11/2004
11	Proteins (Proteins, Gene)FDA Link 04/2022 - 01/2004
11	CalciumIBA 02/2021 - 01/2004
11	SaltsIBA 01/2014 - 06/2003
10	EnzymesIBA 01/2022 - 01/2004
10	Oxidants (Oxidizing Agents)IBA 01/2021 - 01/2006
10	BilirubinIBA 01/2021 - 01/2007
10	Folic Acid (Vitamin M)FDA LinkGeneric 01/2021 - 01/2006
10	Pharmaceutical PreparationsIBA 01/2015 - 01/2005
9	Nonesterified Fatty Acids (NEFA)IBA 12/2021 - 06/2002
9	Fatty Acids (Saturated Fatty Acids)IBA 01/2016 - 06/2002
9	Insulin-Like Growth Factor I (IGF-1)IBA 12/2015 - 06/2003
8	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2021 - 06/2003
8	phycocyanobilinIBA 01/2021 - 03/2009
8	SalicylatesIBA 10/2014 - 12/2005
8	Parathyroid Hormone (Parathormone)IBA 07/2014 - 01/2004
7	Thioctic Acid (Lipoic Acid)IBA 01/2021 - 01/2006
7	Protein Isoforms (Isoforms)IBA 01/2021 - 01/2004
7	Taurine FDA Link 01/2021 - 01/2004
6	Phosphotransferases (Kinase)IBA 04/2021 - 01/2006
6	MagnesiumIBA 01/2021 - 01/2005
6	Peroxynitrous Acid (Peroxynitrite)IBA 01/2021 - 01/2007
6	Complement System Proteins (Complement)IBA 02/2019 - 05/2010
6	Fish OilsIBA 08/2018 - 01/2004
6	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 08/2014 - 06/2006
5	Biotin (Vitamin H)FDA Link 01/2021 - 01/2006
5	CitrullineIBA 01/2021 - 06/2010
5	Glycine (Aminoacetic Acid)FDA LinkGeneric 02/2019 - 08/2009
5	Superoxides (Superoxide)IBA 11/2015 - 06/2002
5	Nitric Oxide Synthase (NO Synthase)IBA 01/2015 - 06/2002
5	LDL CholesterolIBA 01/2015 - 06/2002
5	Triglycerides (Triacylglycerol)IBA 01/2015 - 01/2004
5	BerberineIBA 01/2015 - 12/2009
5	PhytochemicalsIBA 10/2014 - 01/2004
5	DiglyceridesIBA 01/2006 - 01/2005
4	Transcription Factors (Transcription Factor)IBA 04/2022 - 06/2002
4	Sirtuin 1IBA 02/2022 - 11/2015
4	fibroblast growth factor 21IBA 04/2021 - 09/2014
4	PhycocyaninIBA 01/2021 - 03/2010
4	CytokinesIBA 01/2021 - 08/2009
4	Phosphates (Orthophosphate)IBA 01/2021 - 03/2014
4	SeleniumIBA 01/2021 - 12/2004
4	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 01/2021 - 03/2017
4	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2018 - 01/2012
4	Interleukin-6 (Interleukin 6)IBA 08/2016 - 12/2004
4	LipidsIBA 02/2016 - 01/2004
4	Hormones (Hormone)IBA 04/2015 - 01/2004
4	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2015 - 05/2003
4	Angiotensin IIIBA 03/2010 - 01/2004
3	Estrogens (Estrogen)FDA Link 04/2022 - 01/2006
3	Glucosamine (Dona)IBA 02/2022 - 01/2019
3	Mechanistic Target of Rapamycin Complex 1IBA 04/2021 - 10/2011
3	Glutathione (Reduced Glutathione)IBA 01/2021 - 01/2007
3	Acetylcysteine (Siran)FDA LinkGeneric 01/2021 - 01/2010
3	InterferonsIBA 12/2020 - 05/2020
3	Transforming Growth Factor beta (TGF-beta)IBA 08/2020 - 01/2006

Therapy/Procedure

24	Therapeutics 08/2020 - 06/2002
7	Vegan Diet (Diet, Vegan) 04/2021 - 06/2002
7	Plant-Based Diet 05/2020 - 07/2010
5	Glycemic Control 09/2020 - 06/2002
4	Oral Administration 09/2020 - 09/2010
4	Fat-Restricted Diet (Diet, Fat Restricted) 01/2005 - 01/2004
3	Drug Therapy (Chemotherapy) 03/2021 - 09/2006